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Within this framework, the absence of an association between weight loss magnitude and CV outcomes in the present analysis supports the concept that semaglutide may confer CV benefit through mechanisms beyond weight reduction alone

If you take an oral contraceptive, you should use a barrier method (such as condoms) for 4 weeks after starting Mounjaro and for 4 weeks after each dose increase, or switch to a non-oral method of contraception

Whereas the STEP 1 trial delivered semaglutide with wrap around care

Using functional MRI (fMRI), it has been demonstrated that brain regions involved in reward processing are altered in obese individuals [286]

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